The Maryland SPCA is governed by a Board of Directors comprised of volunteers who care about the welfare of animals. They work diligently to ensure the mission of the Maryland SPCA is carried out to its fullest capabilities.
| Jay West President |
Ken Aneckstein Clarke Bessent Toby Broadus Barb Clapp Dr. John Fioramonti Jonathan Gargiulo George R. Grose II David Imre |
Sharon Kroupa Louisa Murphy Charlotte Robinson Patti Sterling Jeff Sube Delegate Shawn Tarrant Sally Thorner Chris Wright |
| Nancy Dorman Christina Lundquist Vice-Presidents |
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| Elizabeth Drigotas Treasurer |
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| Randy Befumo Secretary |